Biogenic Synthesis of Silver Nanoparticles (AgNPs) using Solanum indicum Linn

Abstract: Background: Synthesis of silver nanoparticles (AgNPs) using green plants is important for biocompatibility, reduced hazards, policy and eco-friendliness. Materials Methods: In this study, a leaf extract Solanum indicum associated AgNPs were used to examine larvicidal properties other biological activities. AgNP forms characterized with scanning electron- microscopy (SEM), Fourier Transform Infrared Radiation spectroscopy (FTIR) UV-vis spectra. Larvicidal activity was assessed Culex pipiens larvae the World Health Organization method. Antibacterial potential S. evaluated well diffusion assay. vitro impacts studied spleen cell propagation. Results: ethanol show against 4th instar Cx. pipiens. Synthesized more toxic, lower lethal concentration values, (LC50 = 47.181 ppm; LC90 243.776ppm) compared plant 131.448 4397.528 ppm) after twenty-four hour exposure. also significant impact Staphylococcus aureus, Proteus mirabilis, Escherichia coli Shigella flexneri. Cytotoxic effects demonstrated on normal cells. The safe red blood cells (RBCs) failed cause substantial elevation in serum liver enzymes. Conclusion: Leaf extracts may be efficient eco-friendly control Their antibacterial useful if care taken prevent cytotoxic effects. Key words: effect, pipiens, Silver Nanoparticles, Antibacterial, Larvicidal, indicum.